Best Vitamin B6 Supplements 2026: Cost per Effective Dose
Top pick for Vitamin B6: Nutricost Vitamin B6 (Pyridoxine HCl) 25 mg (240 Capsules) — 25mg B6 per 1 capsule, $0.05/day.
Registry check · Vitamin B6
Does anyone independently verify Vitamin B6 supplements?
We did not find these products in the NSF, USP or Informed Sport registries. 1 display a named mark we could not find in the matching registry. A factory-level claim such as “cGMP” audits the plant, not the Vitamin B6 bottle you would actually receive.
The 12 products on this page checked against all 5,317 US NSF, USP and Informed Sport listings, 2026-08-25. Full method and limitations.
What Vitamin B6 labels show
Priced per day, these vitamin B6 products run $0.05 to $0.31 — a 6.2× gap between the cheapest and dearest vitamin B6 here, across 9 brands.
Which row that favours is not obvious: Nutricost Nutricost Vitamin B6 (Pyridoxine HCl) 25 mg (240 Capsules) is cheapest per serving at $0.05, but its serving sits below the median here, so part of that price gap is simply a smaller capsule.
All Vitamin B6 Supplements Compared
| Product | Brand | Dose / Serving | Cost / Day | Certification (as labelled) | Pick | Buy |
|---|---|---|---|---|---|---|
| Nutricost Vitamin B6 (Pyridoxine HCl) 25 mg (240 Capsules) | Nutricost | 25mg B6 / 1 capsule | $0.05 | None | Buy | |
| Nature's Bounty Vitamin B6 100 mg (100 Tablets) | Nature's Bounty | 100mg B6 / 1 tablet | $0.05 | None | Buy | |
| Nutricost Vitamin B6 (Pyridoxine HCl) 100 mg (240 Capsules) | Nutricost | 100mg B6 / 1 capsule | $0.05 | None | Buy | |
| NOW Vitamin B-6 (Pyridoxine HCl) 100 mg (250 Capsules) | NOW Foods | 100mg B6 / 1 capsule | $0.05 | None | Buy | |
| Solgar Vitamin B6 25 mg (100 Tablets) | Solgar | 25mg B6 / 1 tablet | $0.06 | None | Buy | |
| Nutricost P5P Vitamin B6 50 mg (240 Capsules) | Nutricost | 50mg B6 / 1 capsule | $0.07 | None | Buy | |
| Nature Made Vitamin B6 100 mg (100 Tablets, USP) | Nature Made | 100mg B6 / 1 tablet | $0.11 | USP Verified | Buy | |
| NOW P-5-P 50 mg with Magnesium (90 Capsules) | NOW Foods | 33mg B6 / 1 capsule | $0.14 | None | Buy | |
| Country Life P-5-P 50 mg (100 Tablets) | Country Life | 34mg B6 / 1 tablet | $0.15 | None | Buy | |
| Life Extension Pyridoxal 5'-Phosphate 100 mg (60 Capsules) | Life Extension | 100mg B6 / 1 capsule | $0.28 | None | Buy | |
| Pure Encapsulations P5P 50 (180 Capsules) | Pure Encapsulations | 50mg B6 / 1 capsule | $0.29 | None | Buy | |
| Thorne Pyridoxal 5'-Phosphate (180 Capsules) | Thorne | 34mg B6 / 1 capsule | $0.31 | None | Buy |
In-Depth Vitamin B6 Guides
Go deeper on vitamin B6 — by goal, by form, and what the evidence actually supports:
Our Picks
Lowest Cost: Nutricost Vitamin B6 (Pyridoxine HCl) 25 mg (240 Capsules)
25mg B6 per 1 capsule. $0.05/day. 240 servings per container at $11.95.
Nutricost Vitamin B6 (Pyridoxine HCl) 25 mg (240 Capsules) →
The shelf · Vitamin B6
These Vitamin B6 servings are not comparable to each other
Nutricost Vitamin B6 (Pyridoxine HCl) 25 mg (240 Capsules) states 25 mg a serving and Life Extension Pyridoxal 5'-Phosphate 100 mg (60 Capsules) states 100 mg, both occupy one row of the same price column. So Nutricost Vitamin B6 (Pyridoxine HCl) 25 mg (240 Capsules) showing $0.05 a day, the lowest here, may be reporting a smaller serving rather than a better price. Before comparing Nutricost Vitamin B6 (Pyridoxine HCl) 25 mg (240 Capsules) with Thorne Pyridoxal 5'-Phosphate (180 Capsules), check what each calls a serving.
Method: the 12 Vitamin B6 products above, compared on label facts, serving size, servings per container, form, price. Not a dosing recommendation.
How these 12 Vitamin B6 products were ranked
Not one of these 12 vitamin B6 products could be confirmed in the NSF, USP or Informed Sport registries, so verification separates none of them and the ranking falls to cost per day at the labelled serving. Commission does not enter it: the rate is the same whichever vitamin B6 you buy. Full methodology.