Best Digestive Enzymes Supplements 2026: Cost per Effective Dose
Top pick for Digestive Enzymes: Beano Extra Strength (100ct) — 1tablet per 1 tablet at the start of the meal (1-3 by meal size, per label), None claimed, $0.12/day.
All Digestive Enzymes Supplements Compared
All 5 products sorted by cost per clinically-effective daily dose (lowest first). Dose, certification, and pricing verified against NIH DSLD and manufacturer data.
| Product | Brand | Dose / Serving | Cost / Day | Certification | Pick | Buy |
|---|---|---|---|---|---|---|
| Beano Extra Strength (100ct) | Beano | 1tablet / 1 tablet at the start of the meal (1-3 by meal size, per label) | $0.12 | None claimed | Buy | |
| Nutricost Digestive Enzymes 620mg (120ct) | Nutricost | 620tablet / 1 capsule | $0.17 | Vegetarian-friendly (label claim) | Buy | |
| NOW Super Enzymes (90ct) | NOW Foods | 1tablet / 1 capsule | $0.17 | None claimed | Buy | |
| Lactaid Fast Act Caplets (96ct) | Lactaid | 9000tablet / 1 caplet, with the first bite of dairy | $0.20 | None claimed | Buy | |
| Pure Encapsulations Digestive Enzymes Ultra (180ct) | Pure Encapsulations | 391tablet / 2 capsules | $0.74 | Vegetarian (label claim) | Buy |
In-Depth Digestive Enzymes Guides
Go deeper on digestive enzymes — by goal, by form, and what the evidence actually supports:
Our Picks
Lowest Cost: Beano Extra Strength (100ct)
1tablet per 1 tablet at the start of the meal (1-3 by meal size, per label). None claimed. $0.12/day. 100 servings per container at $11.98.
How We Rank Digestive Enzymes Supplements
Every product is evaluated on three criteria:
- Cost per day. Not cost per pill or cost per bottle — what it actually costs per day at the product's labelled serving. Where a category's servings differ in strength we flag it above the table, because cost per day is only comparable when the doses are.
- Third-party certification. USP Verified, NSF Certified for Sport, and ConsumerLab Approved indicate independent testing for purity, potency, and contaminants.
- Bioavailable form. We prioritize products using the specific chemical form shown to be most effective in published research.
Rankings are not influenced by affiliate commissions. We earn the same commission regardless of which product you choose. Read our full methodology.
Personalize Your Digestive Enzymes Choice
Not sure which digestive enzymes supplement is right for you? Use our free tools:
- DNA Supplement Analyzer — upload 23andMe or AncestryDNA data to check for genetic variants affecting digestive enzymes metabolism. Runs entirely in your browser.
- Lab Results Interpreter — enter your blood test values to get personalized dosing recommendations.
- Supplement Stack Builder — build a complete protocol based on your age, sex, medications, and goals.
- Supplement Audit — already taking digestive enzymes? Check if you have the right form and dose.