Best Phosphatidylserine Supplements 2026: Cost per Effective Dose
Top pick for Phosphatidylserine: Doctor's Best Phosphatidylserine (SerinAid) — 100mg phosphatidylserine per 1 capsule, SerinAid® branded raw material (Chemi Nutra, soy-derived, traceable supply chain), $0.25/day.
All Phosphatidylserine Supplements Compared
All 6 products sorted by cost per labelled serving (lowest first). Dose, certification, and pricing verified against NIH DSLD and manufacturer data.
Read the dose column before the price column. Servings in this category are not equivalent — they range from 100 to 400 mg phosphatidylserine per serving. A lower cost per day here can simply mean a smaller serving, so the cheapest row is not automatically the best value.
| Product | Brand | Dose / Serving | Cost / Day | Certification | Pick | Buy |
|---|---|---|---|---|---|---|
| Doctor's Best Phosphatidylserine (SerinAid) | Doctor's Best | 100mg phosphatidylserine / 1 capsule | $0.25 | SerinAid® branded raw material (Chemi Nutra, soy-derived, traceable supply chain) | Buy | |
| NOW Foods Phosphatidyl Serine 100mg | NOW Foods | 100mg phosphatidylserine / 1 capsule | $0.31 | No third-party PS-content testing disclosed; no branded raw material named | Buy | |
| Double Wood Phosphatidylserine 300mg | Double Wood | 300mg phosphatidylserine / 2 capsules | $0.33 | Non-GMO soy, standardized to 20%, HPLC/ISO-17025 tested per brand site | Buy | |
| Swanson Ultra Sunflower Phosphatidylserine (Sharp-PS Green) | Swanson | 100mg phosphatidylserine / 1 softgel | $0.43 | Sharp-PS® Green branded raw material (sunflower-derived, genuinely soy-free, traceable supply chain) | Buy | |
| Jarrow Formulas PS-100 (Sharp-PS) | Jarrow Formulas | 100mg phosphatidylserine / 1 capsule | $0.55 | Sharp-PS® branded raw material (soy-derived, traceable supply chain) | Buy | |
| Nutricost Phosphatidylserine 400mg (Soy-Free) | Nutricost | 400mg phosphatidylserine / 4 capsules | $0.80 | Labeled soy-free; no third-party PS-content testing disclosed | Buy |
In-Depth Phosphatidylserine Guides
Go deeper on phosphatidylserine — by goal, by form, and what the evidence actually supports:
Our Picks
Lowest Cost: Doctor's Best Phosphatidylserine (SerinAid)
100mg phosphatidylserine per 1 capsule. SerinAid® branded raw material (Chemi Nutra, soy-derived, traceable supply chain). $0.25/day. 120 servings per container at $29.99.
How We Rank Phosphatidylserine Supplements
Every product is evaluated on three criteria:
- Cost per day. Not cost per pill or cost per bottle — what it actually costs per day at the product's labelled serving. Where a category's servings differ in strength we flag it above the table, because cost per day is only comparable when the doses are.
- Third-party certification. USP Verified, NSF Certified for Sport, and ConsumerLab Approved indicate independent testing for purity, potency, and contaminants.
- Bioavailable form. We prioritize products using the specific chemical form shown to be most effective in published research.
Rankings are not influenced by affiliate commissions. We earn the same commission regardless of which product you choose. Read our full methodology.
Personalize Your Phosphatidylserine Choice
Not sure which phosphatidylserine supplement is right for you? Use our free tools:
- DNA Supplement Analyzer — upload 23andMe or AncestryDNA data to check for genetic variants affecting phosphatidylserine metabolism. Runs entirely in your browser.
- Lab Results Interpreter — enter your blood test values to get personalized dosing recommendations.
- Supplement Stack Builder — build a complete protocol based on your age, sex, medications, and goals.
- Supplement Audit — already taking phosphatidylserine? Check if you have the right form and dose.