Best Melatonin Supplements 2026: Cost per Effective Dose
Top pick for Melatonin: Nature Made Melatonin 3 mg — 3mg per 1 tablet, USP Verified, $0.05/day. Our best-value pick.
All Melatonin Supplements Compared
All 5 products sorted by cost per labelled serving (lowest first). Dose, certification, and pricing verified against NIH DSLD and manufacturer data.
Read the dose column before the price column. Servings in this category are not equivalent — they range from 0.3 to 3 mg per serving. A lower cost per day here can simply mean a smaller serving, so the cheapest row is not automatically the best value.
| Product | Brand | Dose / Serving | Cost / Day | Certification | Pick | Buy |
|---|---|---|---|---|---|---|
| Nature Made Melatonin 3 mg | Nature Made | 3mg / 1 tablet | $0.05 | USP Verified | Best Value | Buy |
| Natrol Melatonin 1 mg | Natrol | 1mg / 1 tablet | $0.06 | None | Buy | |
| Nature's Bounty Melatonin 3 mg Quick Dissolve | Nature's Bounty | 3mg / 1 tablet | $0.06 | None | Buy | |
| Life Extension Melatonin 300 mcg | Life Extension | 0.3mg / 1 capsule | $0.08 | None | Buy | |
| Life Extension Melatonin 6 Hour Timed Release 300 mcg | Life Extension | 0.3mg / 1 tablet | $0.09 | None | Buy |
Our Picks
Best Value: Nature Made Melatonin 3 mg
3mg per 1 tablet. USP Verified. $0.05/day. 240 servings per container at $10.73.
How We Rank Melatonin Supplements
Every product is evaluated on three criteria:
- Cost per day. Not cost per pill or cost per bottle — what it actually costs per day at the product's labelled serving. Where a category's servings differ in strength we flag it above the table, because cost per day is only comparable when the doses are.
- Third-party certification. USP Verified, NSF Certified for Sport, and ConsumerLab Approved indicate independent testing for purity, potency, and contaminants.
- Bioavailable form. We prioritize products using the specific chemical form shown to be most effective in published research.
Rankings are not influenced by affiliate commissions. We earn the same commission regardless of which product you choose. Read our full methodology.
Personalize Your Melatonin Choice
Not sure which melatonin supplement is right for you? Use our free tools:
- DNA Supplement Analyzer — upload 23andMe or AncestryDNA data to check for genetic variants affecting melatonin metabolism. Runs entirely in your browser.
- Lab Results Interpreter — enter your blood test values to get personalized dosing recommendations.
- Supplement Stack Builder — build a complete protocol based on your age, sex, medications, and goals.
- Supplement Audit — already taking melatonin? Check if you have the right form and dose.