Isopure vs Dymatize ISO100 (2026): Isopure Is the Better Buy

Our pick

Isopure Low Carb

9.0/10

Cost

$2.31 per 25 g protein

Testing

Informed Choice

Check price

 

Dymatize ISO100

Not scored

Cost

$2.54 per 25 g at The Vitamin Shoppe

Testing

Informed Choice

Check price

Why Isopure Low Carb wins

• It costs less per gram of protein. $2.42 per 25 g against $2.54 for ISO100 at the same store, about 5% less. On Isopure’s own store it is $2.31.
• It has no sugar and fewer carbs. 0 g of sugar and 1 g of carbs a scoop, against 1 g and 2 g in ISO100. Both give you 25 g of protein.
• You give up nothing on testing. Both are on the same Informed Choice list.

ISO100 does two things better, and neither is worth paying more for: it has a little less sodium (180 mg against 210 mg), and it adds no vitamins, which only matters if you already take a multivitamin. Its hydrolyzed whey is sold as faster to absorb; that is Dymatize’s claim, and the labels give no reason to pay for it.

The price test: Isopure costs less per 25 g at the same store

Dymatize sells no tubs on its own site, so we priced both powders at the same store, The Vitamin Shoppe, on October 3, 2026 (regular one-time price, no coupon). Isopure Low Carb’s 4.51 lb tub costs $149.99 for 62 scoops of 25 g: $2.42 per 25 g. ISO100’s 5 lb tub costs $179.99 for 71 scoops of 25 g: $2.54 per 25 g.

Isopure’s own store is cheaper still: its 4.51 lb tub is $143.49 ($2.31 per 25 g, October 3, 2026), and its biggest tub, 7.5 lb, is $2.16. Prices change and stores run sales, so check the tub you see: divide the price by its scoops, or use our cost per 25 g check.

Per scoop: the same protein, and Isopure adds vitamins

Both scoops have 25 g of protein from whey isolate. Here is everything else on the two labels.

The blend is the biggest difference. Isopure’s label lists 23 vitamins and minerals, most from the blend, including vitamin B12 at 100%, copper at 70% and chromium at 90% of the Daily Value a scoop. ISO100 has no vitamin blend. If you already take a multivitamin, add the two labels together, or pick ISO100 so you are not doubling up.

Neither is a low-sodium powder: 210 mg a scoop in Isopure and 180 mg in ISO100. If sodium matters to you, Gold Standard has 55 mg on its label (Isopure vs Gold Standard).

See both labels

Isopure’s is the brand’s own label for the 4.5 lb Dutch Chocolate tub. ISO100’s is the label NIH holds for Gourmet Chocolate (5 lb).

Both are whey isolate, which typically has much less lactose than whey concentrate: about 0.5 to 1% against 4 to 8%, by the U.S. Dairy Export Council’s spec sheets (isolate, concentrate). Those are typical values, not the amount in these tubs. Both labels list milk and soy, so neither is safe for a milk allergy.

Both are on the Informed Choice testing list

Informed Choice screens store-bought products for banned substances, at least monthly. It lists a product line, not a tub size or flavor: Isopure as “LOW CARB” and ISO100 as “ISO100 Hydrolyzed Protein Powder (USA)”. Neither is on NSF Certified for Sport. If your sport requires NSF, see which protein powders NSF lists.

Both on the Informed Choice list

Isopure Low Carb on Informed Choice

ISO100 on Informed Choice

If you are comparing ISO100 with Isopure Zero Carb instead: Zero Carb has 0 g of carbs, but we did not find it on any of the 5 lists we search, so we do not link it. Zero Carb vs Low Carb.

Does hydrolyzed whey make ISO100 better?

Not in any way the labels show. Part of ISO100’s protein is hydrolyzed, meaning pre-broken into smaller pieces; the rest is plain whey isolate. Dymatize sells it as faster to absorb. That is the brand’s claim, and our advice does not rest on it. For muscle, neither label gives a reason to expect a different result if you get the same protein. How much you need a day: protein dosage guide.

Who should buy which

• You want the most protein for your moneyIsopure Low Carb

  $2.42 per 25 g against $2.54 at the same store; $2.31 on Isopure’s own store.

• You already take a multivitamin and want to skip extra vitaminsISO100

  It has no added vitamin blend. You pay a little more per gram of protein for that.

• You watch your sodiumNeither; look at Gold Standard

  ISO100 has a little less (180 mg a scoop against 210 mg). Gold Standard has 55 mg on its label.

• You are drug-testedEither

  Both are on Informed Choice. Check that your sport accepts it. If it requires NSF, neither is listed; Gold Standard’s 10 lb tubs are (which tubs).

• You already have a tub, or you would rather get protein from mealsBuy nothing

  Finish the tub you have; switching changes the price, not the result. Powder is a convenient option, not a requirement; food can cover your protein (ISSN 2017).

More comparisons: Isopure vs Gold Standard, Gold Standard vs ISO100, and every protein powder we price.

Sources

1. Labels: Isopure’s own Low Carb Dutch Chocolate label (4.5 lb tub), and the NIH Dietary Supplement Label Database record (ISO100, Gourmet Chocolate, 5 lb).
2. Testing: Informed Choice certified products (both powders), read October 3, 2026.
3. Prices: theisopurecompany.com, regular price for every size, checked October 3, 2026; The Vitamin Shoppe, regular one-time price, Isopure Low Carb and ISO100, checked October 3, 2026. Dymatize sells no tubs on dymatize.com. We print no Amazon prices; Amazon is only where the buy links go.
4. U.S. Dairy Export Council spec sheets: Whey Protein Isolate and Whey Protein Concentrate 80% (typical lactose content).
5. Jäger R, et al. International Society of Sports Nutrition position stand: protein and exercise. J Int Soc Sports Nutr. 2017;14:20. PubMed 28642676