Verified Supplement Data Primary-sourced

Is Kirkland Signature Worth It? Every Label, Graded

By Erin Rose · Published · Reviewed against primary sources · Methodology · About Us

Not medical advice. This grades Costco’s house brand on the labels it files with the NIH, the USP Verified mark, and the absorption trials behind the fish oil. Prices are Amazon reseller prices; Costco warehouse prices are lower and we do not print numbers we cannot verify. We have no relationship with Costco.

Quick answer

Most Kirkland Signature labels state the USP Verified mark. Of the 44 Kirkland Signature supplement labels filed with the NIH, 31 (70.5%) state the USP Verified mark, a rate Nature Made is close to among the brands we compared (61% of 31 tracked products; NOW Foods 1%). The fish oil label states USP Verified too, and it is 57% omega-3 as ethyl esters, the form absorbed at 73% of natural fish oil in one comparison; the Amazon version carries 300 mg of omega-3 in a 1,000 mg softgel.

Compare the labels that state USP Verified (vitamin D3, CoQ10, the multivitamin, calcium, glucosamine) on cost per dose. 13 labels state no USP mark; 75% of the gummy labels state it against 70% of the rest. See all 44 labels →

Kirkland labels USP Verified 70.5% 31 of 44 · NIH filings · 2026-09-18
Fish oil concentration, Costco label57%684 mg omega-3 in a 1,200 mg softgel · ethyl ester
Vitamin D3 2000 IU, per softgel on Amazon$0.022vs $0.069 Nature Made USP · cheaper in the warehouse
On this page
  1. The USP rate
  2. The fish oil
  3. What to buy at Costco
  4. By product
  5. All 44 labels
  6. FAQ

The USP rate on Kirkland labels

Original researchEvery on-market label filed under the brand Kirkland Signature in the NIH Dietary Supplement Label Database on 2026-09-18: 44 labels, read in full for form, serving, Supplement Facts rows and every statement on the pack. USP Verified here means the label itself states the mark; we did not check each product in the USP registry.

USP runs a third-party program for finished supplements. Kirkland labels state the mark on much of the line: 31 of 44 labels state the mark, and among the tablets and softgels that make up the core range the rate is 70%. In our own catalog, Nature Made is at 61% across 31 tracked products; NOW Foods at 1% across 108; Nature’s Bounty at 0% of 26. The Nature Made report card has the same computation for that brand.

Share of tracked products or filed labels carrying USP Verified, by brand
0% 25% 50% 75% 100% Kirkland Signature (44 filed labels) 70.5% Nature Made (31 tracked) 61% Nature's Bounty (26 tracked) 0% NOW Foods (108 tracked) 1%
Kirkland Signature: 70.5% of 44 NIH-filed labels. Nature Made 61% of 31, Nature's Bounty 0% of 26 and NOW Foods 1% of 108 products in our catalog, computed from the catalog. Source: Our Kirkland label census, 2026-09-18; catalog certification fields.
Share of tracked products or filed labels carrying USP Verified, by brand
ItemValue (%)
Kirkland Signature (44 filed labels)70.5%
Nature Made (31 tracked)61%
Nature's Bounty (26 tracked)0%
NOW Foods (108 tracked)1%

A certification statement does not tell you the dose is right for you or which form is best. The fish oil label is a useful example.

How we read the labels

Method: 44 on-market labels returned by the NIH Dietary Supplement Label Database for the brand “Kirkland Signature” on 2026-09-18, read in full. Brand comparison rates are computed live from our catalog’s certification field and cover only the products we track for those brands. What it cannot tell you: Costco warehouse prices, products Costco sells that have not been filed with the NIH, or whether a reseller’s stock is the current lot.

The fish oil label: 57% omega-3 as ethyl esters

The Kirkland fish oil label on file with the NIH, Fish Oil 1200 mg, is a 1,200 mg softgel delivering 684 mg of total omega-3 fatty acids as ethyl esters, two rows of 410 and 274 mg, one softgel a day. The version sold on Amazon, Kirkland Signature Omega-3 Fish Oil Concentrate 1000 mg, is lower still: 300 mg of omega-3 in a 1,000 mg softgel, 30% concentration, against 750 mg in one NOW Foods Ultra Omega-3 softgel or 950 mg in one Sports Research Triple Strength Omega-3. To match one concentrated softgel you take 2.5 Kirkland softgels.

The form matters as much as the concentration. In a 72-volunteer comparison of concentrated fish oil formulations at the same EPA+DHA dose, bioavailability from ethyl esters was 73% of natural fish oil and from re-esterified triglycerides 124% (Dyerberg 2010, PMID 20638827). Ethyl esters need a fatty meal: in a crossover study of 54 adults, a prescription ethyl-ester omega-3 taken with a low-fat meal delivered a quarter of the EPA+DHA that a free-fatty-acid formulation did, and the gap narrowed to 1.3× with a high-fat meal (Davidson 2012, PMID 23312053). The omega-3 forms comparison ranks the alternatives.

Fish oils we track with Kirkland's Amazon listing added, cheapest per 1,000 mg of omega-3 (EPA+DHA or total omega-3 as each label states) first. Basis: Amazon price divided by the omega-3 in the container, so other pages that use EPA+DHA only may show a different figure.
Fish oilPer 1,000 mg omega-3Omega-3 / servingServingsPriceCertificationBuy
Kirkland Signature Omega-3 Fish Oil Concentrate 1000 mg $0.16 300 mg 1200 $56.25 USP Verified (per Costco label) (brand-stated; not confirmed in the public registry) Check price
NOW Foods Ultra Omega-3 $0.21 750 mg 180 $28.94 none stated Check price
Viva Naturals Triple Strength Omega-3 $0.30 2,070 mg 90 $55.96 IFOS 5-Star Check price
Sports Research Triple Strength Omega-3 $0.36 950 mg 90 $30.71 IFOS 5-Star, MSC Certified Check price
Carlson Elite Omega-3 Gems $0.47 1,400 mg 65 $42.42 IFOS 5-Star Check price
Nordic Naturals Ultimate Omega $0.65 1,100 mg 90 $64.56 Not IFOS-enrolled (brand lot reports only) Check price
Sports Research Vegan Omega-3 $0.71 630 mg 60 $26.95 Vegan Certified, Non-GMO Tested Check price
Nordic Naturals Algae Omega (715mg Omega-3, Vegan), 60 Softgels $1.15 585 mg 30 $20.24 Certified Vegan Check price

At the Amazon reseller price Kirkland’s fish oil is $0.16 per 1,000 mg of omega-3, rank 1 of 8; it lists the lowest omega-3 per softgel of any fish oil we track. At the warehouse price it would move up the table, and the concentration and the ethyl-ester form would not.

What to buy at Costco

Product links go to Amazon resellers and we may earn a commission if you buy. It never changes which product we pick or what we say about it; the same items are cheaper in a Costco warehouse. How we choose.

Vitamin D3 2000 IU
Kirkland Signature Extra Strength Vitamin D3 2000 IU $0.022 per softgel
50 mcg (2,000 IU) cholecalciferol in soybean oil, one a day, The NIH filing states USP Verified. The same dose and mark as Nature Made Vitamin D3 2000 IU ($0.069); the dosage guide covers whether 2,000 is your number.

Check price →

CoQ10 300 mg
Kirkland Signature CoQ10 300 mg $0.080 per 100 mg
300 mg ubiquinone in soybean oil, one softgel, The label states USP Verified. Rank 1 of 6 CoQ10 products we track per 100 mg at the Amazon price.

Check price →

Glucosamine 1500 / chondroitin 1200
Kirkland Signature Extra Strength Glucosamine 1500 mg / Chondroitin 1200 mg $0.27 per day
1,500 mg glucosamine HCl and 1,200 mg chondroitin sulfate in two tablets, The label states USP Verified. Note the HCl salt rather than glucosamine sulfate.

Check price →

Daily multivitamin
Kirkland Signature Daily Multi Vitamins & Minerals $0.05 per day
One tablet a day, The label states USP Verified; a Centrum-style formula. Compare the folate and B12 forms against the multivitamin ranking before choosing it over a 400 mcg methylfolate multi.

Check price →

What the labels show, by product

The fish oil: matching one concentrated softgel takes 2.5 Kirkland softgels, per the label figures above. The gummies: 75% of Kirkland’s gummy labels state the USP mark against 70% of the rest of the line, and the calcium gummies (Kirkland Signature Calcium 500 mg with D3 Adult Gummies) list 500 mg of calcium with 3 g of added sugar in two gummies; the calcium ranking compares tablets. Specialty lines: krill oil (120 mg of omega-3 per softgel), ubiquinol, turmeric and the UC-II joint formula state no USP mark. Magnesium: the filed label is magnesium citrate, 250 mg per two softgels, with no USP mark stated; see the cheapest glycinate ranking for another form at a similar price per milligram.

All 44 Kirkland Signature labels filed with the NIH

Every on-market Kirkland Signature dietary supplement label in the NIH database on 2026-09-18: form, serving, the first Supplement Facts rows and whether the label states USP Verified.
LabelFormServingMain rowsUSP VerifiedFiled
Active Vitamin Pack Other 1 Packet(s) Vitamin A 2500 IU; Vitamin C 590 mg; Vitamin D3 500 IU yes 2019
Adult Multivitamin Gummies Gummy 2 Gummie(s) Vitamin A 750 mcg; Vitamin C 30 mg; Vitamin D 20 mcg yes 2020
B12 5000 mcg Cherry Flavor Tablet 1 Tablet(s) Vitamin B12 5000 mcg yes 2022
C 1000 mg Tablet 1 Tablet(s) Vitamin C 1000 mg; Citrus Bioflavonoid Complex 100 mg yes 2022
C 250 mg Tangerine Gummy 2 Gummie(s) Vitamin C 250 mg yes 2020
Calcium 500 mg with D3 Adult Gummies Gummy 2 Gummy(ies) Vitamin D 25 mcg; Calcium 500 mg; Phosphorus 230 mg yes 2020
Calcium 600 mg Tablet 1 Tablet(s) Vitamin D3 10 mcg; Calcium 600 mg yes 2022
Calcium 600 mg + D3 Tablet 1 Tablet(s) Vitamin D 400 IU; Calcium 600 mg yes 2019
Calcium 600 mg with Vitamin D3 Tablet 1 Tablet(s) Vitamin D3 10 mcg; Calcium 600 mg yes 2022
Calcium 600 mg with Vitamin D3 Tablet 1 Tablet(s) Vitamin D3 10 mcg; Calcium 600 mg yes 2023
Calcium Chews Chocolate Flavored Other 1 Piece(s) Vitamin D 200 IU; Vitamin K 40 mcg; Calcium 500 mg no 2019
Calcium Citrate Magnesium and Zinc Tablet 2 Tablet(s) Vitamin D3 20 mcg; Vitamin B6 10 mg; Calcium 500 mg yes 2017
Calcium Citrate with 500 mg of Calcium Tablet 2 Tablet(s) Vitamin D3 800 IU; Vitamin B6 10 mg; Calcium 500 mg yes 2013
Chewable C 500 mg Tangy Orange Taste Tablet 1 Tablet(s) Vitamin C 500 mg yes 2022
Chewable Vitamin C 500 mg Tangy Orange Tablet 1 Tablet(s) Vitamin C 500 mg yes 2019
CoQ10 300 mg Softgel 1 Softgel(s) Coenzyme Q10 300 mg yes 2019
D3 50 mcg (2000 IU) Softgel 1 Soft Gel(s) Vitamin D3 50 mcg yes 2022
Daily Multi Vitamins & Minerals Tablet 1 Tablet(s) Vitamin A 3500 IU; Vitamin C 90 mg; Vitamin D3 400 IU yes 2013
E 180 mg (400 IU) Softgel 1 Softgel(s) Vitamin E 180 mg yes 2023
Energy B-Complex Adult Gummies Gummy 2 Gummie(s) Vitamin B1 0.15 mg; Vitamin B2 3 mg; Vitamin B6 3.5 mg no 2017
Extra Strength Glucosamine 1500 mg Chondroitin 1200 mg Tablet 2 Tablet(s) Glucosamine Hydrochloride 1500 mg; Chondroitin Sulfate Sodium 1200 mg yes 2022
Extra Strength Glucosamine 1500 mg Chondroitin 1200 mg Tablet 2 Tablet(s) Glucosamine Hydrochloride 1.5 Gram(s); Chondroitin Sulfate Sodium 1.2 Gram(s) yes 2019
Extra Strength Glucosamine HCl 1500 mg with MSM 1500 mg Tablet 2 Tablet(s) Glucosamine Hydrochloride 1500 mg; Methyl Sulfonyl Methane 1500 mg yes 2022
Extra Strength Vitamin D3 2000 IU Softgel 1 Softgel(s) Vitamin D3 2000 IU yes 2016
Fast Acting Lactase Other 1 Caplet(s) Lactase 0 NP no 2016
Fiber Capsules Capsule 2 Capsule(s) Soluble Fiber 2 Gram(s); Iron 0.4 mg; Potassium 30 mg no 2019
Fish Oil 1200 mg Softgel 1 Softgel(s) Fish Oil 1200 mg; Docosahexaenoic Acid Ethyl Ester 410 mg; Docosahexaenoic Acid Ethyl Ester 274 mg yes 2019
Glucosamine 1500 mg Chondroitin 1200 mg Tablet 2 Tablet(s) Glucosamine HCl 1.5 Gram(s); Chondroitin Sulfate Sodium 1.2 Gram(s) yes 2013
Glucosamine HCl 1500 mg with MSM 1500 mg Tablet 2 Tablet(s) Glucosamine HCl 1500 mg; MSM 1500 mg yes 2013
Hair, Skin & Nails Strawberry Cream Flavored Coating Tablet 2 Tablet(s) Vitamin A 5000 IU; Vitamin C 60 mg; Vitamin D3 1000 IU no 2019
Krill Oil 500 mg Softgel 1 Softgel(s) Krill Oil 500 mg; Omega-3 Fatty Acids 120 mg; Eicosapentaenoic Acid 60 mg no 2019
Magnesium Citrate 250 mg Softgel 2 Softgel(s) Magnesium Citrate 125 mg no 2019
Ocusight Adult 50+ Softgel 1 Softgel(s) Vitamin C 150 mg; Vitamin E 20.1 mg; Zinc 9 mg no 2020
Optifiber Powder 2 Teaspoon(s) Soluble Fiber 3 Gram(s) yes 2022
Optifiber Powder 2 tsp Soluble Fiber 3 Gram(s) no 2017
Organic Multivitamin Tablet 1 Tablet(s) Vitamin A 945 mcg RAE; Vitamin C 90 mg; Vitamin D3 30 mcg yes 2022
Performance Multi Energy Formula Tablet 1 Tablet(s) Vitamin A 5000 IU; Vitamin C 120 mg; Vitamin D3 400 IU yes 2019
Sugar Free Children's chewable Tablet 0.5 Tablet(s) Vitamin A 1250 IU; Vitamin C 125 mg; Vitamin D3 200 IU yes 2013
Super B-Complex With Electrolytes Tablet 1 Tablet(s) Vitamin C 200 mg; Thiamine 100 mg; Riboflavin 20 mg yes 2016
Super B-Complex with Electrolytes Tablet 1 Tablet(s) Vitamin C 200 mg; Thiamine 100 mg; Riboflavin 20 mg yes 2022
Triple Action Joint Health Tablet 1 Tablet(s) UC-II Proprietary Cartilage Blend 40 mg; undenatured Type II Collagen 0 NP; Boron Glycinate 5 mg no 2020
Turmeric 1000 mg Capsule 2 Capsule(s) Turmeric Root Extract 1000 mg; Black Pepper Fruit Extract 10 mg no 2023
Ubiquinol 200 mg Softgel 1 Softgel(s) Vitamin E 30 IU; Kaneka Ubiquinol 200 mg no 2020
Ultra Strength Antacid Calcium Carbonate 1000 mg Assorted Berry Flavors Tablet 2 Tablet(s) Calcium 800 mg no 2019

Frequently asked questions

How many Kirkland Signature labels state USP Verified?

31 of the 44 Kirkland Signature supplement labels filed with the NIH state the USP Verified mark (70.5%). This is what the labels say; we did not check each product in the USP registry. Among the brands in our catalog, Nature Made has a comparable rate (61% of 31 tracked products); NOW Foods is at 1%. The 13 Kirkland labels without the mark are mostly gummies, chews, fiber and the krill, ubiquinol and turmeric lines.

What does the Kirkland fish oil label say?

The Costco-shelf label filed with the NIH, Fish Oil 1,200 mg, delivers 684 mg of omega-3 per softgel as ethyl esters (57% concentration), and the version sold on Amazon is 1,000 mg fish oil with 300 mg omega-3, 30%. Ethyl-ester fish oil was absorbed at 73% of natural fish oil in a 72-person comparison, against 124% for re-esterified triglycerides, so more softgels and a meal with fat are needed for the same amount. Per 1,000 mg of omega-3 the Amazon-priced Kirkland ranks 1 of 8 fish oils we track; at the warehouse price it is cheaper than that.

Is Kirkland vitamin D3 the same as Nature Made?

Both are 2,000 IU cholecalciferol softgels in soybean oil and both labels state USP Verified. Kirkland's NIH filing is D3 50 mcg (2,000 IU), one softgel a day, USP Verified; Nature Made's 2,000 IU is the same dose and mark. On Amazon Kirkland costs $0.022 a softgel in a five-bottle pack against $0.069 for Nature Made; at the Costco warehouse the Kirkland bottle is cheaper still. Compare the price per softgel.

Which Kirkland labels do not state USP Verified?

13 of the 44 filed labels state no USP mark: Calcium Chews Chocolate Flavored; Energy B-Complex Adult Gummies; Fast Acting Lactase; Fiber Capsules; Hair, Skin & Nails Strawberry Cream Flavored Coating; Krill Oil 500 mg; Magnesium Citrate 250 mg; Ocusight Adult 50+; Optifiber and 4 more. Of Kirkland's gummy labels 75% state the mark, against 70% of everything else; the specialty lines (krill oil, ubiquinol, turmeric, the UC-II joint formula) state no mark.

Is Kirkland CoQ10 worth it?

Kirkland CoQ10 300 mg is ubiquinone in soybean oil, USP Verified, one softgel a day. At the Amazon price it is $0.080 per 100 mg, rank 1 of 6 CoQ10 products we track; the Costco price is lower. The Kirkland Ubiquinol 200 mg, the reduced form, is not USP Verified.

Can I buy Kirkland supplements without a Costco membership?

Yes, through Amazon and other resellers. The prices on this page are Amazon multi-pack prices. Check that the reseller listing shows the USP mark and a lot number; the label filed with the NIH is the reference.

Related guides

Sources

  1. Dyerberg J, et al. “Bioavailability of marine n-3 fatty acid formulations.” Prostaglandins Leukot Essent Fatty Acids. 2010. PMID: 20638827
  2. Davidson MH, et al. “A novel omega-3 free fatty acid formulation has dramatically improved bioavailability during a low-fat diet compared with omega-3-acid ethyl esters: the ECLIPSE study.” J Clin Lipidol. 2012. PMID: 23312053
  3. US Pharmacopeia. USP Verified Mark program requirements. usp.org
  4. NIH Office of Dietary Supplements. Dietary Supplement Label Database, brand “Kirkland Signature”, 44 on-market labels. dsld.od.nih.gov (retrieved 2026-09-18).