Nicotinamide Riboside (NR): Label Facts, Cost and Testing
Two NR supplements had a buyable Amazon listing when we checked, and both are listed in NSF Certified for Sport. Thorne NiaCel 400 has 415 mg nicotinamide riboside hydrogen malate and 85 mg betaine per capsule and costs $1.23 per capsule. Tru Niagen 300mg has 300 mg nicotinamide riboside chloride (Niagen) per capsule and costs $1.63 per capsule. Prices recorded November 6, 2026.
A buyer’s guide to NR labels, cost and testing. Not medical advice.
| Product | Per capsule | Registry listing | Cost per capsule | |
|---|---|---|---|---|
| Thorne NiaCel 400 60 capsules | 415 mg nicotinamide riboside hydrogen malate and 85 mg betaine per capsule | NSF Certified for Sport #1423140, 60-capsule pack listed | $1.23 | Check price → |
| Tru Niagen 300mg 30 capsules | 300 mg nicotinamide riboside chloride (Niagen) per capsule | NSF Certified for Sport #1473227 and #1263423, 30-capsule pack listed | $1.63 | Check price → |
Cost per capsule = Amazon price ÷ capsules. Never ranked by commissions.
Start here
What to check on an NR label
- Which form of NR. Tru Niagen uses NR chloride (sold as Niagen). Thorne NiaCel uses NR hydrogen malate and adds betaine. The milligrams on each label are for that form.
- Capsules per serving. Both products list 1 capsule as a serving.
- A registry listing that covers your pack. NSF Certified for Sport lists Tru Niagen 300 mg in 30-, 60- and 90-capsule packs and NiaCel 400 in the 60-capsule pack.
On this page
What human trials of NR have measured
Human trials of NR have been small (8 to 40 people) and short (21 days to 12 weeks). Most measured NAD+ in blood or muscle, which is a lab measure. Trials that measured other things found no significant difference, or said they were too small to tell.
| Study | People and dose | What was measured | What was found |
|---|---|---|---|
| Martens 2018 PMID 29599478 | 24 adults aged 55 to 79; 1,000 mg a day for 6 weeks | Blood-vessel measures | No significant difference across the group after correction. |
| Dollerup 2018 PMID 29992272 | 40 men; 2,000 mg a day for 12 weeks | How the body handles sugar, energy use and body composition | No difference from placebo. |
| Dollerup 2020 PMID 31710095 | Same group, muscle samples | Muscle mitochondria | No change. |
| Elhassan 2019 PMID 31412242 | 12 older men; 1,000 mg a day for 21 days | Muscle mitochondria | No change in how the mitochondria used oxygen. |
| Wang 2022 PMID 36644285 | 30 adults; 2,000 mg a day for 12 weeks | Walk distance and quality-of-life scores | No significant difference; the authors said the trial was too small to tell. |
If you take any medicine, ask your doctor before you start a new supplement.
Frequently asked questions
What is nicotinamide riboside (NR)?
NR is a form of vitamin B3 sold as a dietary supplement, usually in capsules.
Which NR supplements are third-party tested?
Both NR products we track are listed in NSF Certified for Sport: Tru Niagen 300 mg (listings 1473227 and 1263423, 30-capsule pack listed) and Thorne NiaCel 400 (listing 1423140, 60-capsule pack).
What does NR cost?
Thorne NiaCel 400 costs $1.23 per capsule, and Tru Niagen 300mg costs $1.63 per capsule (Amazon prices on November 6, 2026).
What have human trials of NR measured?
The trials were small and short. Most measured NAD+ in blood or muscle, a lab measure. Trials that measured other things found no significant difference, or said they were too small to tell.
Related guides
Sources
- NSF Certified for Sport listings 1473227, 1263423 and 1423140, read 2026-10-01.
- Supplement Facts panels on the Amazon listings and Amazon prices, read 2026-10-01. Dataset: /nr/cost-by-brand.json (CC BY 4.0).
- Martens CR, et al. Nature Communications. 2018. PMID: 29599478
- Dollerup OL, et al. Am J Clin Nutr. 2018. PMID: 29992272
- Dollerup OL, et al. J Physiol. 2020. PMID: 31710095
- Elhassan YS, et al. Cell Reports. 2019. PMID: 31412242
- Wang DD, et al. JACC: Basic to Translational Science. 2022. PMID: 36644285