Verified Supplement Data Primary-sourced

Health Condition Supplement Protocols — Evidence-Based

By Erin Rose · Updated · Methodology · About Us

What are condition protocols? Each protocol is a complete, evidence-ranked supplement plan for a specific health condition. We review the clinical trial literature (RCTs and meta-analyses), rank every supplement by strength of evidence, and provide specific product recommendations with clinical doses, timing, drug interaction warnings, and cost per day.

Condition Protocols

Supplements for Anxiety and Depression (2026)

Evidence-ranked supplement protocol for anxiety and depression. Magnesium, omega-3, ashwagandha, vitamin D, and SAMe ranked by clinical evidence level. Medication interactions, dosing, and cost per day.

Supplements for Joint Pain & Arthritis (2026)

Evidence-ranked supplement protocol for joint pain and arthritis. Curcumin, glucosamine, chondroitin, omega-3, and collagen ranked by meta-analysis evidence. Medication interactions, dosing, cost per day.

PCOS Supplements (2026): Evidence-Ranked Protocol

Evidence-ranked supplement protocol for PCOS based on 46 RCTs. Myo-inositol, vitamin D, NAC, berberine, and omega-3 with clinical doses, timing, and drug interaction warnings.

Best Supplements for Stress (2026)

The three with real trial evidence: ashwagandha (lowered cortisol ~28% in an RCT), magnesium glycinate, and L-theanine. Doses, timing, what to skip, interactions, and cost per day.

Best Supplements for Fatigue & Low Energy (2026)

The honest, test-first protocol: supplements fix fatigue only when they correct a deficiency. Iron (low ferritin), B12, vitamin D, magnesium — plus why most "energy" pills do nothing.

Best Supplements for Immune Support (2026)

Vitamin D to prevent, zinc lozenges to shorten a cold. What the evidence actually supports for vitamin C and probiotics, the doses, and what to skip.

Best Supplements for Bloating (2026)

Match the supplement to the type of bloating: peppermint oil for IBS-type, probiotics for flora-linked, magnesium for constipation-driven. Evidence, doses, and when to see a doctor.

Coming Soon

We are actively developing evidence-ranked protocols for additional conditions:

  • Hair Loss Coming Soon — Iron, biotin, vitamin D, saw palmetto, and the ferritin threshold most doctors miss.
  • ADHD Coming Soon — Omega-3 (EPA-dominant), iron, zinc, magnesium, and vitamin D evidence for focus and attention.
  • Menopause Coming Soon — Black cohosh, magnesium, vitamin D, omega-3, and phytoestrogen evidence for hot flashes and bone loss.
  • Thyroid Coming Soon — Selenium, iodine, zinc, vitamin D, and iron for hypothyroidism and Hashimoto's.

Personalized Tools

Get supplement recommendations tailored to your individual data:

  • DNA Supplement Analyzer — Upload your 23andMe or AncestryDNA data to find which supplement forms your genetics need.
  • Lab Results Interpreter — Enter your blood test values for a personalized supplement protocol with specific products and doses.
  • Supplement Recommender — Answer questions about your goals, medications, and diet for a custom protocol.