Vitamin D: What It Does, How Much You Need and What to Buy
Most adults need 600 to 800 IU of vitamin D a day, and a 1,000 to 2,000 IU vitamin D3 supplement covers it. Vitamin D helps your body absorb calcium to keep bones strong. Our pick: NatureWise D3 2000 IU, on NSF/ANSI 173, about 4 cents a day.
By Erin Rose Updated October 20, 2026 How we score
What to buy
NatureWise D3 2000 IU is our pick: one small softgel of vitamin D3 a day, on the NSF/ANSI 173 testing list. Of the 19 products we score, 7 are on a testing list. If your doctor wants you on 5,000 IU, or you want K2, a lower price or a vegan spray, see the best vitamin D for your needs.
NatureWise D3 2000 IU
4 cents a day · 2,000 IU · NSF/ANSI 173
Where to go next
- Best vitamin D: our pick and the best one for each need.
- Vitamin D dosage guide: how much to take for your age and situation.
- Third-party tested vitamin D: which bottles are on a testing list.
- Vitamin D3 prices: every bottle we track, cheapest per dose first.
- Best vitamin D3 K2 supplement: the D3 + K2 combos compared by testing.
- D2 vs D3, with or without K2, 1,000 vs 5,000 IU and D3 5000 IU with K2.
- Nature Made vs NOW Foods: two big brands side by side.
- Signs you are low and the vitamin D blood test.
- Best time to take it, side effects and the IU to mcg chart.
- Vitamin D for seniors and for women.
What vitamin D does
Your body needs vitamin D to absorb calcium from food, which keeps bones strong. Your skin makes it in sunlight, and a few foods have it. Here is what trials found when people took it as a supplement.
| Goal | Evidence | What trials found |
|---|---|---|
| Bones | Good, with calcium | Taken daily with calcium, it lowered fractures by 6% and hip fractures by 16% (Yao 2019). Taken alone by healthy adults, it did not prevent fractures (LeBoff 2022). |
| Prediabetes | Some | In three trials pooled together, 4,000 IU a day lowered the chance of getting diabetes by about 15% (Pittas 2023). Ask your doctor before taking a dose that high. |
| Colds and chest infections | Mixed | Early reviews found a small drop, mostly with daily doses. The 2025 update of 40 trials found the drop too small to be sure of (Jolliffe 2025). |
| Autoimmune disease | Some | In a 5-year trial, 22% fewer people got an autoimmune disease while taking it (Hahn 2022). The effect faded after they stopped. |
| Falls | No benefit | It did not prevent falls in 81 trials (Bolland 2018). One huge dose once a year raised falls (Sanders 2010), so take a small daily dose instead. |
| Depression and mood | No benefit | It did not prevent depression in 18,353 adults (Okereke 2020). |
| Cancer and heart disease | No benefit | 2,000 IU a day for about five years did not lower cancer, heart attacks or strokes in 25,871 adults (Manson 2019). |
Who runs low on vitamin D?
About 1 in 5 US adults (21%) has a blood level below 50 nmol/L, the level the NIH calls enough for most people, and about 1 in 20 (5.5%) is below 30 nmol/L, which is deficient. That is from our own analysis of the newest national blood data (NHANES 2021–2023).
Younger adults run low most often: 31% of adults 18 to 39 are below 50 nmol/L, against 10% of adults 60 and over. You are also more likely to run low if you have darker skin, carry extra weight, get little sun, or have a condition that blocks fat absorption, like Crohn’s or celiac disease. Breastfed babies need 400 IU a day. A blood test tells you your level; see the vitamin D test.
How long does vitamin D take to work?
Blood levels climb for about two to three months on a steady daily dose, then level off. In a careful winter study, each extra 1,000 IU a day raised blood levels by about 7 ng/mL (Heaney 2003). People who start low rise more, and people with obesity rise less.
How much to take
Adults need 600 IU a day up to age 70 and 800 IU after that. The upper limit for adults is 4,000 IU a day from all sources. Pick vitamin D3, which raises blood levels more than D2, and take it with a meal. The dosage guide has the dose for your situation.
Is vitamin D safe?
Yes, at 1,000 to 2,000 IU a day, for most adults. Too much vitamin D is rare and almost always comes from very large doses or a labeling mistake. It raises calcium in the blood, which causes nausea, thirst and confusion. Ask your doctor or pharmacist first if you:
- Take a thiazide water pill, a steroid like prednisone, orlistat or a statin.
- Have sarcoidosis, kidney disease or high calcium.
- Want to add K2 and take warfarin; see with or without K2.
Questions people ask
Can I test my vitamin D at home?
Yes. Home kits mail a finger-prick blood sample to a lab, which measures the same 25-hydroxyvitamin D a doctor’s test does. Most healthy adults do not need a test before taking 1,000 to 2,000 IU. The vitamin D blood test.
Does vitamin D help with seasonal depression?
Trials say no: large studies found vitamin D does not prevent depression (Okereke 2020). Light therapy for seasonal low mood is a separate treatment, with its own lamps and research; ask your doctor about it.
Can you get too much vitamin D from the sun?
No. Your skin stops making vitamin D once it has enough. Too much vitamin D almost always comes from very large supplement doses.
Sources
- NIH Office of Dietary Supplements, “Vitamin D: Fact Sheet for Health Professionals.” ods.od.nih.gov
- CDC, National Health and Nutrition Examination Survey 2021–2023, serum 25-hydroxyvitamin D (our survey-weighted analysis of US adults).
- Yao P, et al. “Vitamin D and calcium for the prevention of fracture: a systematic review and meta-analysis.” JAMA Netw Open. 2019. PubMed 31860103
- LeBoff MS, et al. “Supplemental vitamin D and incident fractures in midlife and older adults.” N Engl J Med. 2022. PubMed 35939577
- Pittas AG, et al. “Vitamin D and risk for type 2 diabetes in people with prediabetes: a systematic review and meta-analysis of individual participant data from 3 randomized clinical trials.” Ann Intern Med. 2023. PubMed 36745886
- Jolliffe DA, et al. “Vitamin D supplementation to prevent acute respiratory infections: systematic review and meta-analysis of stratified aggregate data.” Lancet Diabetes Endocrinol. 2025. PubMed 39993397
- Hahn J, et al. “Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial.” BMJ. 2022. PubMed 35082139
- Bolland MJ, et al. “Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis.” Lancet Diabetes Endocrinol. 2018. PubMed 30293909
- Sanders KM, et al. “Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial.” JAMA. 2010. PubMed 20460620
- Okereke OI, et al. “Effect of long-term vitamin D3 supplementation vs placebo on risk of depression or clinically relevant depressive symptoms and on change in mood scores: a randomized clinical trial.” JAMA. 2020. PubMed 32749491
- Manson JE, et al. “Vitamin D supplements and prevention of cancer and cardiovascular disease.” N Engl J Med. 2019. PubMed 30415629
- Heaney RP, et al. “Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol.” Am J Clin Nutr. 2003. PubMed 12499343