{ "dataset": "citrus-bergamot-cost-by-brand", "title": "Citrus Bergamot (BPF) Supplements Compared — standardization disclosure, dose vs trial range, and cost per mg", "sourcePage": "https://verifiedsupplementdata.com/citrus-bergamot/best-overall/", "license": "CC-BY-4.0", "licenseUrl": "https://creativecommons.org/licenses/by/4.0/", "attribution": "Verified Supplement Data (2026), Citrus Bergamot Cost Comparison", "dateModified": "2026-07-19", "methodology": "Only 1 of 6 tracked citrus bergamot products discloses a polyphenol standardization percentage on the label — that product is ranked first regardless of price, because standardization (not raw cost per mg) is the primary honest ranking axis for this ingredient: the human trials tested a specific standardized bergamot polyphenolic fraction (BPF) material, and an unstandardized \"bergamot extract Xmg\" label cannot be verified to match it. costPerMg = price / (servings x mg per serving), computed on total extract weight, not polyphenol-adjusted (5 of 6 products don't disclose that figure). \"verdict\": standardized (label prints a polyphenol %), unstandardized (in the ~500-1000mg/day typical trial/retail dose range but no % disclosed), low-dose-caution (mg/day sits near 500mg, the dose that produced NO effect in the one null trial in this pack, Bruno 2017, PMID 28443024), high-dose-caution (mg/day exceeds 1300mg, the highest dose tested in any trial in this pack, Capomolla 2019, PMID 31167512). EVIDENCE CONTEXT (promising-but-low-quality, YMYL category — not a statin-replacement claim): most positive human trials for bergamot polyphenols and LDL/triglyceride/HDL come from a small cluster of Italian research groups with commercial or institutional ties to the extract (Mollace/Magna Graecia University of Catanzaro = BPF originator; several Cicero/Bologna-group trials funded by Meda-Mylan/Scharper/Esserre Pharma). The one clearly independent systematic review (Lamiquiz-Moneo 2020, PMID 31670973, 12 studies) found real signal but stated study quality was \"quite limited.\" Citrus bergamia is grapefruit-family and contains furanocoumarins that can inhibit CYP3A4, the pathway that metabolizes many statins — anyone on a statin or other CYP3A4-metabolized medication should talk to a clinician before adding a bergamot supplement. This statement has not been evaluated by the FDA; these products are not intended to diagnose, treat, cure, or prevent any disease.", "headline": { "productsCompared": 6, "standardizedDisclosed": 1, "unstandardized": 3, "standardizedPickBrand": "Citrus Bergamot 150:1", "standardizedPolyphenolPct": 70, "lowDoseCautionBrand": "NusaPure", "highDoseCautionBrand": "tnvitamins", "typicalDoseRangeMg": [ 500, 1000 ], "highestTestedDoseMg": 1300, "note": "The cheapest cost-per-mg products in this set are also the two dose-flagged caution picks (one below, one above the trial-tested range) — cheap and flagged should not be read as a top pick. The one standardized product is the headline recommendation despite not being the cheapest." }, "columns": [ "brand", "product", "slug", "form", "mgPerServing", "polyphenolPct", "activePolyphenolMg", "servings", "price", "costPerServing", "costPerMg", "verdict", "certification" ], "units": { "mgPerServing": "mg bergamot extract", "activePolyphenolMg": "mg polyphenols (where disclosed)", "price": "USD", "costPerServing": "USD/serving", "costPerMg": "USD per mg of extract" }, "citations": [ { "claim": "Systematic review of 12 human studies: 75% showed significant LDL/TC/TG improvement, but \"studies had heterogeneous designs and scientific quality of studies was quite limited.\"", "source": "Lamiquiz-Moneo A, et al. 2020, Critical Reviews in Food Science and Nutrition", "pmid": "31670973" }, { "claim": "BPF 1000mg/day enhanced rosuvastatin's LDL-lowering effect in an open-label, placebo-controlled trial (n=77); Mollace/Catanzaro group, BPF-originator institution.", "source": "Gliozzi M, et al. 2013, International Journal of Cardiology", "pmid": "24239156" }, { "claim": "Low-dose BPF (500mg/day, 60 days) did NOT improve metabolic parameters in antipsychotic-treated patients — the one null trial in this pack.", "source": "Bruno A, et al. 2017, Frontiers in Pharmacology", "pmid": "28443024" }, { "claim": "\"The evidence of benefits of berberine and bergamot is not so conclusive\" and \"the opinion of experts on berberine and bergamot is ambiguous.\"", "source": "Kłosiewicz-Latoszek L, et al. 2021, Annals of Agricultural and Environmental Medicine", "pmid": "33775071" } ], "products": [ { "brand": "Citrus Bergamot 150:1", "product": "Extract, 70% Polyphenols, Italian Sourced (1200mg)", "slug": "citrus-bergamot-150-1-70-polyphenols-1200mg", "form": "Capsule (150:1 extract)", "mgPerServing": 1200, "polyphenolPct": 70, "activePolyphenolMg": 840, "servings": 60, "price": 21.95, "costPerServing": 0.37, "costPerMg": 0.0003, "verdict": "standardized", "note": "70% polyphenols disclosed on label — the only product in this comparison with a printed standardization percentage, and the closest label match to the standardized BPF material used in the clinical trials.", "certification": "None claimed" }, { "brand": "Nutricost", "product": "Citrus Bergamot 1200mg (2x600mg Capsules)", "slug": "nutricost-citrus-bergamot-1200mg", "form": "Capsule", "mgPerServing": 1200, "polyphenolPct": null, "activePolyphenolMg": null, "servings": 60, "price": 14.95, "costPerServing": 0.25, "costPerMg": 0.0002, "verdict": "unstandardized", "note": "Not disclosed — no polyphenol percentage printed on the label.", "certification": "None claimed" }, { "brand": "Secret Element", "product": "Citrus Bergamot Extract 1000mg", "slug": "secret-element-citrus-bergamot-1000mg", "form": "Veg capsule", "mgPerServing": 1000, "polyphenolPct": null, "activePolyphenolMg": null, "servings": 120, "price": 23.97, "costPerServing": 0.2, "costPerMg": 0.0002, "verdict": "unstandardized", "note": "Labeled “polyphenol-rich” with no percentage disclosed — standardization is unverifiable from the label.", "certification": "None claimed" }, { "brand": "Double Wood", "product": "Citrus Bergamot 1000mg (Bergamonte Standardization, NSF Certified)", "slug": "double-wood-citrus-bergamot-1000mg", "form": "Capsule", "mgPerServing": 1000, "polyphenolPct": null, "activePolyphenolMg": null, "servings": 60, "price": 24.95, "costPerServing": 0.42, "costPerMg": 0.0004, "verdict": "unstandardized", "note": "Branded “Bergamonte Standardization” is claimed, but no polyphenol percentage is printed on the label — the standardization method is undisclosed and cannot be verified against the trial material (BPF/Bergavit).", "certification": "NSF Certified" }, { "brand": "tnvitamins", "product": "Citrus Bergamot 2000mg", "slug": "tnvitamins-citrus-bergamot-2000mg", "form": "Capsule", "mgPerServing": 2000, "polyphenolPct": null, "activePolyphenolMg": null, "servings": 180, "price": 15.99, "costPerServing": 0.09, "costPerMg": 0, "verdict": "high-dose-caution", "note": "Not disclosed. Also flagged for dose: 2000mg/day exceeds the highest dose tested in any trial in this pack (1,300mg/day, Capomolla 2019 high-dose arm) — more milligrams is not shown to mean more benefit, especially with zero standardization disclosed.", "certification": "None claimed" }, { "brand": "NusaPure", "product": "Citrus Bergamot 600mg", "slug": "nusapure-citrus-bergamot-600mg", "form": "Veg capsule", "mgPerServing": 600, "polyphenolPct": null, "activePolyphenolMg": null, "servings": 200, "price": 24.99, "costPerServing": 0.12, "costPerMg": 0.0002, "verdict": "low-dose-caution", "note": "Not disclosed. Also flagged for dose: 600mg/day sits close to the 500mg/day dose that produced NO metabolic effect in the one null BPF trial in this evidence pack (Bruno 2017).", "certification": "None claimed" } ] }